Acyclovir : Drug Information

What is Acyclovir?

Acyclovir is an antiviral drug commonly known as synthetic nucleoside analogues and used to treat infections caused by specific types of viruses. This medication is a treatment for cold sores around the mouth (caused by herpes simplex), chickenpox, and shingles (caused by herpes zoster). It is also the prevention of outbreaks of Genital Herpes. Sometimes it is used to treat outbreaks of genital herpes in those infected with the virus.

This medication stops the spread of the herpes virus in the body. It is not a cure for genital herpes, and it can not control the spread of genital herpes to others. It just slows the growth and spread of Genital Herpes in the individual’s body.

Important information

Complete the full course of this therapy, your symptoms may stop showing, but your infection stay remains the same.

Immediately start the Acyclovir therapy, as soon as you recognize infection symptoms, such as burning, tingling, blisters, etc.

Infections through herpes are contagious, and others may infect by the infectious body. The Acyclovir can not stop you from containing herpes infections and from infecting others. Do not let someone get into contact with the infected area. You should also avoid touching the infected area and then your eyes without washing your hands.

Wash your hands frequently to stop passing the infection to others. When you are using this medication, drink plenty of fluids.

What to know before taking Acyclovir?

This medication is not for you if you are allergic to Acyclovir or Valacyclovir (Valtrex). If you are allergic to milk proteins, you may not take the Acyclovir buccal tablet.

Be careful before taking this medication. Read all the instructions related to dosing, uses, and precautions printed on the package label.

To make sure Acyclovir is right for you or not, tell your doctor before taking this medication if you have or ever had;

  • a weak immune system (caused by particular medicine or by disease).
  • kidney disease

Before taking this medication, consult with your doctor if you are breastfeeding.

Before taking this medication, talk to your doctor if you are pregnant or planning to become pregnant.

Acyclovir is not for a child younger than two years old. So please do not give it to your children without consulting your doctor.

If you are weak from your immunity system, please consult with your doctor before using this medicine. If you have a dehydration problem due to any illness or have ever had HIV or AIDS, please tell your doctor about it.

If you are taking this medication to relieve genital herps, keep in mind that herps can pass from your body to your partner’s body during sexual contact. Please consult with your doctor about stopping herps from passing to your partner; they will tell you what to do.

How to take Acyclovir?

Take this medication according to your prescription; do not take it unnecessarily. This medication is for treating disease, so do not take this medication in a large amount or beyond your prescribed doses.

Follow all the directions printed on the package label or written on the medication guide that comes with the medicine.

Start Acyclovir therapy as soon as you see the first appearance of the symptoms such as burning, tingling, blisters. If you notice a cold sore appearance, start taking Sitavig within one hour.

If you have any confusion about this medicine’s uses or doses, immediately consult with your doctor and then start to use this medicine precisely as your doctor prescribes you to take.

Do not chew, suck on, crush, or swallow Acyclovir buccal tablet. Place the Acyclovir buccal tablet in your mouth. The flat side of the tablet should be against your upper gum and the same side as your cold sore.

Do not give a buccal tablet to the child younger than two years old; choking may occur.

When you will measure the dosage of this medication’s oral suspension form, first properly shake it and then use the medicine dosage-measuring device or the dosing syringe that comes with the medicine. If you do not have a dosing syringe or medicine dose-measuring device aks your pharmacist for this.

Please regularly go to your doctor for regular checkups because the dosage of Acyclovir depends on your weight, so it may be required to change your doses if you gain or lose some weight.

Take water in excess during Acyclovir treatment so that your kidneys work properly.

Complete the full length of Acyclovir therapy and take this medication for the entire length of prescription. Do not stop taking this medicine suddenly. If you want to stop taking this medicine, consult with your doctor. They will tell you the proper way of stopping Acyclovir treatment.

You may feel well within one or two days after you start taking this medication. Do not stop taking this medicine when your symptoms are not visible to you because if you stop taking it before the complete treatment of your disease, your symptoms may come back again, and maybe your condition may become worse. So please complete the full length of your therapy.

Please keep your wounds caused by herps clean and dry as much as possible. Loose clothing will help you to prevent irritation due to your injuries.

Store this medicine in a dark place, at room temperature, and keep it away from heat and moisture.

Acyclovir Dosage

Usual Recommended Dosage of Acyclovir for Adults

To treat the first episode of genital herpes, the CDS recommended usual dosage is 400mg orally three times every 24 hours for at least 5 to 10 days,

The manufacturer’s recommendation for the dosage is 200mg orally every four hours, five times a day for ten days.

For the severe disease, the recommended dosage is 5mg/kg for every eight hours for the five days, or 5mg to 10mg /kg for every eight hours for two to seven days until your doctor observes any clinical improvement.

Please consult with your doctor for detailed information about Acyclovir medication.


If you take this medicine in a large amount, immediately seek emergency medical attention, or you should directly call on the Poison Help line number 1-800-222-1222.

Do not take this medicine in excess, and if you forget to take any scheduled dosage, you may take it as soon as you remember the missed dosage. If your next dosage is near to take, please skip the missed one, do not take a double dosage of this medicine; it may become fatal for your medical health.

What to avoid while using Acyclovir?

Avoid chewing gum, brushing your teeth, or wearing an upper denture while using a buccal tablet in your mouth. You should rinse your mouth softly and take plenty of water or other liquids to prevent dry mouth.

You can infect other peoples; even you are taking Acyclovir regularly according to your prescription because the herps infections are contagious. Avoid touching your eyes if you think you feel the infected area and not let people connect it. Frequently wash your hands with Sanitizer or soap to prevent the spread of the infection.

Avoid sexual intercourse if you are suffering from genital herpes infection because, during sexual intercourse, genital herpes may transfer to your partner’s body.

Acyclovir side effects

The severe side-effects of this medication are;

  • difficult breathing
  • signs of an allergic reaction to Acyclovir: hives
  • swelling of your face, lips, tongue, or throat

Consult with your therapist if you feel the symptoms such as;

  • easy bruising or bleeding
  • changes in behavior
  • confusion
  • hallucinations
  • little or no urinating
  • painful or difficult urination
  • purple or red pinpoint spots under your skin;
  • swelling in your feet or ankles
  • feeling tired or short of breath
  • mild skin pain
  • rash, itching
  • nausea, vomiting, diarrhea
  • headache
  • mouth pain while using buccal tablets.

What drugs can interact with Acyclovir?

Acyclovir is harmful to your kidneys, especially when using certain medications for cancer, infections, organ transplant rejection, bowel disorder, osteoporosis, or arthritis or pain, such as Tylenol, Advil, Aspirin, and Aleve.

Vitamins and Herbal products may also interact with this medication; talk with your therapist about your current medication and tell them in detail what kind of drugs you are using and why you are taking.

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