Baclofen : Drug Information

What is Baclofen?

Baclofen is a muscle relaxer medication and also acts as an antispasmodic agent.

Baclofen can treat spasms, muscle pain, and stiffness in people with various sclerosis or spinal cord disease or injury.

You can take Baclofen intrathecally orally (by mouth) or (directly into the spinal cord).

Baclofen is a prescription medication used to heal spasticity from multiple sclerosis, particularly for the relief of concomitant and spasms pain, muscular rigidity, and clonus. Your doctor may prescribe Baclofen alone or with other medications.

Baclofen relates to a class of drugs known as Skeletal Muscle Relaxants.

It is unknown that Baclofen is safe and effective for infants younger than 12 years of age.

Important Information

Do not use this medication simultaneously when you need muscle tone for safe balance and movement during specific actions. Do not drive or operate complex machinery until you recognize how this medication affects you.

Do not stop using this drug suddenly, or you could suffer from unpleasant withdrawal symptoms.

Baclofen comes in tablet form and a solution (liquid) to use by mouth. Doctors generally prescribe this medication to take three times a day at evenly separated intervals. Follow all the directions on your medicine label strictly, and request your doctor or pharmacist to clarify any part you do not recognize. Take Baclofen precisely as directed. Please do not use this medicine more or less or take it more regularly than your doctor prescribed.

Use an oral syringe (measuring device) to scale and take your dosage of Baclofen solution correctly. Request your pharmacist for an oral syringe if it is not with your medication.

Continue to take Baclofen even if you observe healthily. Do not stop taking Baclofen without communicating with your doctor, particularly if you have taken high doses for a long time. Abruptly discontinuing this medication can cause fever, confusion, muscle stiffness, seizures, or hallucinations. Your doctor apparently will want to reduce your dosage gradually.

What to know before taking Baclofen?

You should not take Baclofen if you are allergic to this medication.

To make sure this remedy is safe for you, inform your physician if you have ever had:

  • epilepsy or other seizure disorder
  • mental illness or psychosis
  • a nervous system disorder
  • a stroke or blood clot
  • kidney disease.

Using Baclofen may raise your risk of producing an ovarian cyst. Discuss with your doctor about your particular risk.

Inform your physician if you are pregnant or breastfeeding.

If you use Baclofen throughout pregnancy, your newborn baby may suffer from some withdrawal symptoms such as rigid muscles, tremors, or a seizure. Follow your doctor’s directions about reducing your dosage as your due date comes.

If you use this medication while you are breastfeeding, withdrawal signs may happen in the nursing baby. Request your doctor if it is secure for you to breastfeed while using this medicine.

Baclofen is not for the use of anyone who is younger than 12 years old.

Inform your physician or pharmacist what different prescription and nonprescription medications, nutritional supplements, vitamins, and herbal products you are using or plan to take. Be sure to consider any of the following: antidepressants, drugs for anxiety, medications for seizures, sedatives, sleeping pills, medicines for mental illness, or tranquilizers. Your doctor may suggest you change your prescriptions’ doses or monitor you carefully for side effects.

How to take Baclofen?

Take this medicine exactly as your doctor prescribes you. Follow all regulations on your prescription label and read all medicine instruction sheets or guides. Your physician may occasionally change your dosage.

Shake the oral suspension (liquid) before measuring a dose. Use the dosing syringe that comes with your medicine, or measure your dosage with a dose-measuring device (not a kitchen spoon).

Ask your therapist if your muscle signs do not improve or if they get more serious.

It would be helpful if you did not stop taking Baclofen suddenly, or you could have severe or fatal withdrawal signs. Obey your doctor’s directions about tapering your dose.

Store Baclofen at room temperature away from heat and moisture.

Baclofen dosage

The dosage of this medication entirely depends on your medical condition, so your doctor will suggest you the doses of this medicine according to your problem. Please follow all the dosage directions of your doctor.

The usual dosage of this medication may need to increase gradually. Here is a standard dosage increment for adults;

  • 5mg three times every day for three days
  • 10mg three times every day for three days
  • 15mg three times every day for three days
  • 20mg three times every day for three days

After that, an additional dosage increment may be necessary, but the total daily dosage should not exceed a maximum of 80mg daily means 20mg divided doses three times a day.


Seek emergency medical consideration or call the Poison Help line number at 1-800-222-1222.

Overdosing symptoms may involve severe dizziness, drowsiness, vomiting, muscle weakness, dilated or pinpoint pupils, seizure, shallow breathing, or loss of consciousness.

What to avoid while using Baclofen?

Do not use Baclofen simultaneously when you need muscle tone for safe movement and balance during specific actions. In some circumstances, it may be critical for you to have decreased muscle tone.

Drinking alcohol with Baclofen can produce some severe side effects.

Avoid driving or hazardous actions until you know how this drug will affect you. This medication can impair your reactions.

Baclofen side effects

Get emergency medicinal help if you have symptoms of an allergic reaction to this medicine, such as difficulty breathing, hives, swelling of your tongue, face, lips, or throat.

Talk to your physician at once if you suffer from;

  • confusion, hallucinations
  • severe drowsiness, weak or shallow breathing
  • itching, tingling or twitching in your arms, feet, hands, or legs
  • fever
  • a seizure

Common Baclofen side effects may involve;

  • headache
  • drowsiness, dizziness, weakness, tiredness
  • sleep problems (insomnia)
  • urinating more often than usual
  • nausea, constipation

The above is not a complete list of all possible side-effects. Talk to your therapist for medical advice about all possible side-effects. You may report side-effects to FDA at 1-800-FDA-1088.

What drugs can interact with Baclofen?

Using Baclofen with other medicines that make you drowsy or slow your breathing may cause serious side-effects, or your death may occur.

Tell your health care provider if you are taking any of the following medicines:

  • Opioid medications
  • Sleeping pills
  • Muscle relaxers
  • Medicines for depression, anxiety, or bipolar disorder
  • Seizure medication
  • Blood pressure medication

Other drugs also can interact with Baclofen, including prescription or over-the-counter medications, vitamins, and herbals. Take advice from your doctor about all your current medicines and any prescription medication you start or stop taking.

Check the descriptions on all your prescriptions (such as cough-and-cold or allergy products) because they may include ingredients that make you sleepy. Talk to your druggist about taking those products securely.

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