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Benazepril : Drug Information

What is Benazepril?

Benazepril is a prescription drug that comes as an oral tablet.

It is available as a brand-name drug called Lotensin. Benazepril also comes as a generic drug.

Benazepril is an ACE inhibitor that doctors prescribe to treat high blood pressure (hypertension). Lowering blood pressure may reduce your risk of a stroke or heart attack.

Doctors often combine this drug with other medications to use it as part of combination therapy. That means you may need to take it with other medicines.

Benazepril also finds its uses for purposes not listed in this medication guide.

Important Information

Avoid using Benazepril if you are pregnant. You should stop taking Benazepril if you become pregnant and should inform your doctor immediately.

Avoid using this medicine if you have ever had angioedema. You should also not take Benazepril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

Do not use this medicine in combination with any medication that contains aliskiren (a blood pressure medicine) if you have diabetes.

What to know before taking Benazepril?

You should avoid using Benazepril if you feel allergic using it, or in the below conditions:

  • If you have hereditary angioedema
  • If you lately took a heart medicine called sacubitril.
  • If you have ever had a severe allergic reaction to any ACE inhibitor

Ace inhibitors include captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril.

Doctors advise not to take this medicine within 36 hours before or after taking a medication containing sacubitril (such as Entresto).

People with diabetes should not use this medicine together with any medication that contains aliskiren (a blood pressure medicine).

Avoid consuming Benazepril with aliskiren if you have kidney disease.

Consult with your doctor if you have ever had:

  • Liver disease
  • Kidney disease
  • An organ transplant
  • Heart disease

Avoid using Benazepril during pregnancy. If you become pregnant, completely stop taking this medicine and tell your doctor immediately. Benazepril can cause severe injury or death to the unborn baby if you take medicine during your second or third trimester.

Do not breast-feed while you are using Benazepril.

Doctors disapprove of the use of Benazepril by anyone younger than six years old.

How to take Benazepril?

While using Benazepril, follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally alter your dose depending on the condition. Use the medicine exactly as directed by medical practitioners.

You can take Benazepril with or without food.

It would be best if you kept in mind to drink plenty of water each day while you are taking Benazepril.

Your doctor might often check your blood pressure and your kidney function.

Get a doctor’s help if you are suffering from vomiting or diarrhea or sweating more than usual. You can quickly become dehydrated while taking this medicine. It can lead to reduced blood pressure, electrolyte disorders, or kidney failure while taking Benazepril.

If you need surgery, tell the surgeon ahead of time that you are using Benazepril.

You should keep using this medicine as directed by your doctor, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

Benazepril dosage

It might not be possible to mention all dosages and drug forms here. Your dosage, drug form, and dosage intensity may vary depending upon:

  • Your age
  • The condition to treat
  • The severity of your condition
  • Other medical conditions you have
  • How you react to the first dose

Dosage for high blood pressure

Adult dosage (ages 18 to 64 years)

  1. The typical dosage is 10 mg tablet by mouth once daily.
  2. The maintenance dosage is 20 to 40 mg once daily or in two equally divided doses.

Child dosage (ages 6 to 17 years)

  1. The typical dosage is 0.2 mg/kg once daily.
  2. It’s important to note that children in this age group shouldn’t consume this drug if their creatinine clearance (CrCl) is less than 30 mL/min/1.73 m2.

Child dosage (ages 0 to 5 years)

Doctors do not recommend this medication for children younger than six years of age.

Senior dosage (ages 65 years and above)

Old age people suffer from kidney problems. It can lead to the body processing drugs more slowly. As a result, a higher amount of drugs stays in the body for a longer time, increasing the risk of side effects even more.

Your doctor may begin with a low dosage or a different dosing schedule to help prevent levels of this drug from building up too much in your body.

Overdose

It’s uncommon to see human overdoses of Benazepril. Still, the most common manifestation of its overdosage in humans is likely to be hypotension. Hypotension is associated with electrolyte disturbances and renal failure.

While using Benazepril, consider dialysis to support patients with severely impaired renal function.

If ingestion is recent, consider activated charcoal. Consider gastric decontamination (e.g., vomiting, gastric lavage) in the early period after ingestion.

You should monitor blood pressure regularly. In the case of marked hypotension, consider using vasopressors.

It would be best if you immediately get emergency medical attention or call the Poison Help line at 1-800-222-1222 in case of overdose symptoms.

What to avoid while using Benazepril?

You should avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Also, avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Benazepril can decrease sweating, and you may be more prone to heatstroke.

Refrain from drinking alcohol because it can lower your blood pressure and increase Benazepril’s specific side effects.

Unless your doctor advises, do not use potassium supplements or salt substitutes along with Benazepril.

Benazepril side effects

You should seek emergency medical help if you develop signs of:

  • An allergic reaction like hives, severe stomach pain, difficulty in breathing, swelling in your face or throat
  • Severe skin reaction, including fever, sore throat, burning in your eyes, skin pain, a red or purple skin rash that spreads and causes blistering and peeling.

Contact your doctor immediately if you have:

  • Difficulty urinating
  • Feeling light-headed
  • High potassium leading to nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement
  • Liver problems, stomach pain (upper right side), loss of appetite, dark urine, jaundice (yellowing of the skin or eyes)

Common side effects may include:

  • Headache, or
  • Cough

The above-stated list is not a complete list of side effects and may include several other side effects. In case of any of these side effects, call your doctor for medical advice. You may also report side effects to FDA @ 1-800-FDA-1088.

What drugs can interact with Benazepril?

You should ensure to let your doctor know of all your current medications. Many drugs can affect Benazepril, notably:

  • Lithium
  • A diuretic (“water pill”) or any other blood pressure medications
  • Insulin or oral diabetes medicine
  • gold injections to treat arthritis
  • NSAIDs–ibuprofen(Advil, Motrin), aspirin, diclofenac, naproxen (Aleve), meloxicam, indomethacin, celecoxib, and others.

The above-stated list is not complete and may include drugs that may affect Benazepril. It includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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