What is Bicalutamide?

Bicalutamide is available under the brand name called Casodex. It is a type of antiandrogen. Doctors prescribe this medication to treat prostate cancer. Doctors use this medication together with a gonadotropin-releasing hormone (GnRH) analog or surgical removal of the testicles to treat advanced prostate cancer. It is also beneficial to treat excessive hair growth in women, as a component of feminizing hormone therapy for transgender women, to treat early puberty in boys, and prevent overly long-lasting erections in men.

Bicalutamide works by blocking the male hormone (testosterone), which reduces the growth and spread of cancer-causing cells. It is mostly available in the oral form. One can avail of this medication only with a proper prescription from a doctor.

Important Information

  • You must visit your doctor regularly and take a proper body checkup to avoid unwanted medicines effects.
  • Please don't stop taking Bicalutamide without consulting your doctor; otherwise, you may face unpleasant withdrawal symptoms.
  • Please avoid medical errors.
  • It will be best if you take frequent blood tests while you are on this medication.
  • Doctors should not prescribe Bicalutamide to women and children.

What to know before taking Bicalutamide?

You should avoid taking this medication if you are allergic to it or any of its components. To ensure that Bicalutamide is safe for you, you should tell your doctor if you have or ever had the following medical issues:

  • Liver disease
  • Diabetes
  • The problem in the blood clotting

Doctors should prescribe this medication only to men. It may also cause congenital disabilities if the father is using it when his sexual partner becomes pregnant. Male patients and their partners should use adequate contraception during treatment with this medicine and 130 days after the last dose. If you think your female partner has become pregnant while using this medicine, consult your doctor immediately.

How to take Bicalutamide?

Take Bicalutamide precisely as prescribed by the doctor. You must follow all the directions given on the prescription label and medication guide carefully. Please don't take it more than recommended and try to be consistent throughout the treatment. Consult your doctor if you are not feeling any improvement in the condition or getting worse. Keep the medication out of children's reach and store it at room temperature away from heat and moisture. After completion of treatment, ask your pharmacist regarding the disposal of leftover medicines.

Bicalutamide dosage

The dosage of Bicalutamide prescribed by the doctor is dependent on several factors, such as :

  • The age and weight
  • Symptoms
  • The seriousness of the condition
  • Another medical problem that the patient is having
  • Other medications that the patient is using
  • How the patient reacted to the first dose of the medication

The doctor may prescribe you the dosage of Bicalutamide according to the patient's different medical conditions.

For prostate cancer

In the oral form

  • For adults (above 18 years of age)

50 mg of Bicalutamide once a day, in the morning or evening.

  • For children (below 18 years of age)

Doctors should not recommend Bicalutamide for children.


There are no specific Bicalutamide overdose symptoms, but if you ever feel uneasy after taking this medication, you can consult your doctor and ask for medical help. You can seek medical assistance by calling the poison helpline at 1-800-222-1222.

What to avoid while using Bicalutamide?

Taking Bicalutamide may impair your thinking and reaction; you should avoid getting involved in those activities that require attention and alertness. Avoid direct exposure to sunlight while you are on this medication.

Bicalutamide side effects

Some of the common side effect symptoms of using Bicalutamide are as follows:

  • Anemia
  • Blood in urine
  • Fever
  • Chills
  • Symptoms of flu
  • Trouble in breathing
  • Hot flashes
  • Pain in back
  • Pain in pelvis
  • Pain in stomach
  • Swelling in arms, legs, ankles, or feet
  • Frequent urination during the night
  • Weakness
  • Dizziness
  • Nausea or vomiting
  • Constipation
  • Allergic reaction to the medicine

It is obvious to experience mild side effect symptoms, but if these symptoms bother you so much and are unbearable, you should consult your doctor and ask for medical help. You can stop taking medication and tell your doctor if you face the following problems while taking Bicalutamide:

  • Pain or swelling in the breast
  • Sudden chest pain
  • Wheezing while breathing
  • Dry cough
  • Shortness of breath
  • Symptoms of anemia such as pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands, and feet.
  • Unusual bruising or bleeding
  • A liver problem such as upper stomach pain, feeling tired, loss of appetite, dark urine, clay-colored stools, nausea, jaundice, chills, fever.
  • High blood sugar level resulting in increased thirst, increased urination, dry mouth, fruity breath odor

You should also report to your doctor from time to time if you experience any new symptoms or your symptoms are getting even worse.

What drugs can interact with Bicalutamide?

If your doctor is treating you with Bicalutamide, he must be knowing all the possible interactions with other medications. It will be best to tell your doctor about all the over-the-counter medicines you take or taken in the past few days. Some of the following medications which can interact with Bicalutamide are:

  • Warfarin
  • Acenocoumarol
  • Domperidone
  • Phenprocoumon
  • Piperaquine
  • Herbal products
  • Vitamins or other nutritional supplements