Morphine : Drug Information

What is Morphine?

Morphine is a drug used to treat moderate to severe pain. It belongs to the categories of medicines called opioids. Sometimes opioids are also called narcotics. Morphine is a substance found naturally in various plants, animals, and even humans.

Do you know what Opioids are?

An opioid is a broad group of various pain-relieving drugs that reduce your pain feeling by interacting with opioid receptors presented in your body cells.

When opioids medicines attack opioid receptors of your brain cells, the brain cells start releasing signals that reduce your painful feelings and increase your feelings of pleasure. When doctors prescribe opioids for a specific reason, it safely helps control acute pain when taken a specified amount.

How does Morphine reduce your painful feelings?

Morphine works on the central nervous system directly and decreases the intensity of your painful feelings. It is an enormously effective medication in acute and chronic pain. In the medication field, it is frequently used for myocardial infarction and labor pain.

How long does Morphine take to start its action?

Morphine can administer in various forms. The two standard methods are taken through the mouth or injection across multiple body parts. When it is injected into the body parts, the effect of Morphine is fast. It starts acting after 20 minutes when administered intravenously. It takes a long time to start its action (60 minutes) when administered orally.

How long does Morphine stay in the body?

Generally, the effect of Morphine remains 3 to 7 hours in the body, but a long-acting formulation of this medication also exists.

Do you know Morphine is a habit-forming medication?

Morphine is a pain-reducing medication that blocks the pain sensation and calms some central nervous system’s functions by decreasing the heart rate. Morphine is beneficial when it is taken according to your doctor’s prescription. But when it is taken improperly, you may feel dependency on it or become addicted to Morphine.

Since Morphine is an opioid, so it has a strong tendency of habit-forming. If you take this medication in excess that is not required for your body or consume it regularly, you will feel an addiction to this medication.

What to know before taking Morphine?

  • You should not take Morphine if you suffer from any kind of allergic reaction to it or any other opioid.
  • If you have severe asthma or breathing problems, this medication may be harmful to you.
  • Please consult with your doctor and tell them about your asthma and breathing problem’s stage and severity.
  • Morphine is not for you if you are using MAO inhibitors for the last 14 days. The interaction of Morphine with the MAO inhibitor is hazardous.
  • MAO inhibitor contains isocarboxazid, linezolid, methylene blue injection, rasagiline, phenelzine, selegiline, tranylcypromine, and many other chemicals. If you take Morphine when you are using an MAO inhibitor, a dangerous interaction with these chemicals occurs, and you may get in a life-threatening situation.
  • Talk with your prescription to make sure that Morphine affects you positively if you have or ever had;
    • head injury
    • brain tumor
    • seizures
    • breathing problems
    • sleep apnea
    • drug or alcohol addiction
    • mental illness
    • urination problems
    • liver or kidney disease
    • problems with your thyroid or gallbladder.
  • If you are taking Morphine during pregnancy, this medicine affects your baby and can make your baby dependent. Means Morphine becomes an essential chemical for your newborn’s body.
  • If you are breastfeeding your baby, do not take Morphine. It will enter your newborn’s body through breast milk and cause breathing problems and drowsiness in your baby. The death of your newborn may occur.

How to take Morphine?

  • Take Morphine precisely the same according to your doctor’s prescription. Follow all the directions of your prescription and read the full medication guide before using this medicine.
  • Do not use Morphine in a large amount or longer than the prescription; it may be life-threatening for you.
  • If you feel a strong urge for this medication or take an excessive amount, immediately leave to take this medication and go to your doctor to consult with him.
  • Sharing an opioid medication with others, especially those who are or ever had a drug abuser, is harmful to them. Maybe Morphine is not a requirement of their body, and these medicines raise a life-threatening situation.
  • Keep this medicine out of the reach of children or others. Reselling or giving Morphine to others is against the law.
  • If you are taking other narcotic pain relief medications, stop taking them if you are using Morphine.
  • Morphine comes as a liquid, an extended-release tablet, and an extended-release capsule that can be taken orally. If you cannot understand the dosages of Morphine, talk to your doctor, and get clear about dosages.
  • If you are prescribed Morphine in a solution form, use the syringe or dosing cup that comes with the medicine to measure the amount to take. Be sure that you take your medication in the same amount as your doctor prescribed you to take.
  • The Kadian brand of an extended-release capsule can be administered by a surgically inserted feeding tube (gastrostomy tube). Consult with your doctor to know how to take this medicine through a gastrostomy tube.
  • If you can not swallow the extended-release capsule, you can open it, sprinkle all of its beads, and drink the whole mixture immediately without chewing or crushing the beads. Rinse your mouth with a little water, consume the water, and make sure you have eaten potent medicine. Mixing the beads into any eatables may be dangerous.
  • Your doctor may increase or decrease your dosages gradually according to need. If you suddenly stop taking this medication, you may feel some withdrawal symptoms such as teary eyes, runny nose, restlessness, anxiety, sweating, and many more.

Morphine dosage

Morphine is not a commonly used medication since it is an opioid, so do not misuse it. If you have any questions about dosages, please meet your doctor and clear your doubts.

Morphine is usually prescribed to take once a day. But it may be increased or decreased according to t your body needs. Since this medication is used to relieve pain, you should not miss any dose of it. If by mistake you forget to take a dose of Morphine, take it immediately when you remember. Now you can take your next dosage as follows:

  • If you are taking Morphine 3 times a day: there should be at least an 8 hours gap between your previous and next dosage.
  • If you are taking Morphine 2 times a day: there should be at least a 12 hours gap between your previous and next dosage.
  • If you are taking Morphine 1 time a day: take your medicine 24 hours from the missed one.

Do not take two doses simultaneously. Do not take Morphine more than your prescribed dosage.


A morphine overdose can be dangerous, especially in a child or for those who use it without a prescription. In the condition of overdose, you may feel some symptoms that indicate your overdosing. These indications include:

  • slow heart rate
  • muscle weakness
  • severe drowsiness
  • cold, clammy skin, pinpoint pupils
  • muscle weakness
  • prolonged breathing, or coma

What to avoid while using Morphine?

Drinking alcohol during this medication is not suitable for your health. Taking alcohol with Morphine may show some dangerous side-effects. This act may put you in a life-threatening situation; your death may occur.

Avoid driving or heavy machinery operation until you know how this medication affects you. You may feel Dizziness or Drowsiness that can lead you to an accident or severe injuries.

Morphine side effects

You have to get emergency medical help if you feel an allergic reaction to Morphine, like hives, difficult breathing, swelling of your lips, face, tongue, or throat.

Morphine can slow your breathing even if it can stop your breathing. If you feel slow breathing, having long pauses, or if you are hard to wake up or blue colored lips, it is suggested that in these circumstances, please ask your neighbor immediately to take you to the nearest hospital.

Get an appointment with your healthcare provider if you are feeling;

  • slow heart rate
  • sighing,
  • weak or shallow breathing,
  • breathing that stops during sleep;
  • chest pain,
  • fast or pounding heartbeats;
  • extreme drowsiness,
  • feeling like you might pass out;
  • nausea,
  • vomiting,
  • loss of appetite,
  • dizziness,
  • worsening tiredness or weakness.

Severe Side-effects of Morphine are;

  • agitation
  • hallucination
  • fever
  • sweating
  • shivering
  • fast heart rate
  • muscle stiffness
  • twitching
  • loss of coordination
  • nausea
  • vomiting
  • diarrhea

What drugs can interact with Morphine?

Morphine can interact with many other drugs and produce side-effects that are severe to your health. The other drugs that interact with Morphine are;

Sedative drugs like;

  • Valium
  • diazepam
  • alprazolam
  • lorazepam
  • Ativan
  • Klonopin
  • Restoril
  • Tranxene
  • Versed
  • Xanax, and others

drugs that make you sleepy or slow your breathing

  • a sleeping pill
  • muscle relaxer
  • tranquilizer
  • antidepressant, or antipsychotic medicine

drugs that affect serotonin levels in your body

  • a stimulant, or medicine for depression
  • Parkinson’s disease
  • migraine headaches
  • serious infections, or prevention of nausea and vomiting.

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